Publications
A complete list of Dr. Lamming’s Publications can be found on Pubmed
Dietary Branched-Chain Amino Acids in Aging and Age-Related Disease
Dietary Macronutrients and Calories in Healthy Aging
mTOR, Rapalogs, and other Geroprotectors
- Restriction of Individual Branched-Chain Amino Acids has Distinct Effects on the Development and Progression of Alzheimer’s Disease in 3xTg Mice, Advanced Science, 2026 PDF
- Dietary isoleucine content modulates the metabolic and molecular response to a Western diet in mice, Molecular Metabolism, 2025 PDF
- Tissue-Specific Effects of Dietary Protein on Cellular Senescence Are Mediated by Branched-Chain Amino Acids, Aging Cell, 2025 PDF
- Late-life protein or isoleucine restriction impacts physiological and molecular signatures of aging, Nature Aging, 2024 PDF
- Dietary restriction of isoleucine increases healthspan and lifespan of genetically heterogeneous mice, Cell Metabolism, 2023 PDF
- Protein restriction and branched-chain amino acid restriction promote geroprotective shifts in metabolism, Aging Cell, 2022 Review PDF
- The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine, Cell Metabolism, 2021 PDF
- Lifelong restriction of dietary branched-chain amino acids has sex-specific benefits for frailty and life span in mice, Nature Aging, 2021 PDF
- Restoration of metabolic health by decreased consumption of branched-chain amino acids, Journal of Physiology, 2018 PDF
- Decreased Consumption of Branched-Chain Amino Acids Improves Metabolic Health, Cell Reports, 2016 PDF
- Fasting is required for many of the benefits of calorie restriction in the 3xTg mouse model of Alzheimer’s disease, Nature Communications, 2025 PDF
- A nutrigeroscience approach: Dietary macronutrients and cellular senescence , Cell Metabolism, 2024 Review PDF
- Non-canonical metabolic and molecular effects of calorie restriction are revealed by varying temporal conditions, Cell Reports, 2024 PDF
Protein restriction slows the development and progression of pathology in a mouse model of Alzheimer’s disease , Nature Communications, 2024 PDF
- Quantification of healthspan in aging mice: introducing FAMY and GRAIL , GeroScience, 2024 PDF
- Resistance exercise protects mice from protein-induced fat accretion , Aging Cell, 2023
- When a calorie is not just a calorie: Diet quality and timing as mediators of metabolism and healthy aging, Cell Metabolism, 2023 Review PDF
- FGF21 has a sex-specific role in calorie-restriction-induced beiging of white adipose tissue in mice, Aging Biology, 2023 PDF
- Regulation of metabolic health by dietary histidine in mice , Journal of Physiology, 2023 PDF
- Sex and genetic background define the metabolic, physiologic, and molecular response to protein restriction, Cell Metabolism, 2022 PDF
- Fasting drives the metabolic, molecular and geroprotective effects of a calorie-restricted diet in mice, Nature Metabolism, 2021 PDF
- Calorie Restriction-Induced Insulin Sensitivity Is Mediated by Adipose mTORC2 and Not Required for Lifespan Extension, Cell Reports, 2019
- Bench to bedside: is rapamycin headed for the docTOR?, Geroscience, 2026 Review PDF
- Rapamycin Does Not Compromise Exercise-Induced Muscular Adaptations in Female Mice, Aging Cell, 2025 PDF
- Acarbose ameliorates Western diet-induced metabolic and cognitive impairments in the 3xTg mouse model of Alzheimer’s disease, Geroscience, 2024 PDF
- Blazing a trail for the clinical use of rapamycin as a geroprotecTOR, Geroscience, 2023
- Targeting the biology of aging with mTOR inhibitors, Nature Aging, 2023 Review PDF
- The central moTOR of metabolism, Developmental Cell, 2022 Review
- Ovariectomy uncouples lifespan from metabolic health and reveals a sex-hormone-dependent role of hepatic mTORC2 in aging, eLife, 2020
- A novel rapamycin analog is highly selective for mTORC1 in vivo, Nature Communications, 2019
- Hypothalamic mTORC2 is essential for metabolic health and longevity, Aging Cell, 2019
- Rapamycin blocks induction of the thermogenic program in white adipose tissue, Diabetes, 2016
- Intermittent administration of rapamycin extends the lifespan of female C57BL/6J mice, JGBS, 2016
- Alternative rapamycin treatment regimens mitigate the impact of rapamycin on glucose homeostasis and the immune system, Aging Cell, 2015
- Sex- and tissue-specific changes in mTOR signaling with age in C57BL/6J mice, Aging Cell, 2015